Description

Ethyl 4-(4-Methoxyphenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the polyfunctionalized hexahydroquinoline class. This compound is valued for its role as a key synthetic building block in the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for process development and scale-up.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of complex drug candidates, particularly those with potential biological activity.
• Organic Synthesis Building Block: Used in multi-step synthesis for constructing polycyclic frameworks due to its reactive ester and ketone functionalities.
• Medicinal Chemistry Research: Employed in lead optimization and structure-activity relationship (SAR) studies for new therapeutic agents.
• Agrochemical Development: Acts as an intermediate in the research and production of advanced crop protection agents.
• Fine Chemical Production: Utilized in the manufacture of specialty chemicals requiring a defined hexahydroquinoline core structure.

Basic Information

Item	Details
Product Name	Ethyl 4-(4-Methoxyphenyl)-2,7,7-Trimethyl-5-Oxo-1,4,5,6,7,8-Hexahydroquinoline-3-Carboxylate
CAS No.	181480-21-7
Molecular Formula	C22H27NO4
Molecular Weight	369.46 g/mol
Synonyms	Ethyl 4-(4-methoxyphenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydro-3-quinolinecarboxylate; 1,4,5,6,7,8-Hexahydro-4-(4-methoxyphenyl)-2,7,7-trimethyl-5-oxo-3-quinolinecarboxylic acid ethyl ester; 3-Quinolinecarboxylic acid, 1,4,5,6,7,8-hexahydro-4-(4-methoxyphenyl)-2,7,7-trimethyl-5-oxo-, ethyl ester; Hantzsch ester derivative; Polyhydroquinoline derivative
EINECS	Contact for details

Quality Control

Our Ethyl 4-(4-Methoxyphenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.