Description

8-Chloro-2-Phenylquinoline-4-Carboxylic Acid is a high-purity, synthetically valuable quinoline derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both chlorophenyl and carboxylic acid functional groups, makes it an essential intermediate for the development of novel active compounds. This product is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for creating new molecules with targeted biological activities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for anti-inflammatory, antiviral, or anticancer research programs.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, or insecticides, leveraging the bioactive quinoline scaffold.
• Material Science Research: Serves as a monomer or ligand precursor for creating functional polymers, metal-organic frameworks (MOFs), or advanced catalytic systems.
• Organic Light-Emitting Diodes (OLEDs): Investigated as a core structure for electron-transporting or emissive materials in electronic device fabrication.
• Chemical Biology Probes: Utilized to develop fluorescent tags or molecular probes for studying biological processes and enzyme interactions.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and discovery chemistry projects.

Basic Information

Product Name	8-Chloro-2-Phenylquinoline-4-Carboxylic Acid
CAS No.	181048-56-6
Molecular Formula	C16H10ClNO2
Molecular Weight	283.71 g/mol
Synonyms	8-Chloro-2-phenylquinoline-4-carboxylic acid; 2-Phenyl-8-chloroquinoline-4-carboxylic acid; 4-Quinolinecarboxylic acid, 8-chloro-2-phenyl-; 181048-56-6; 8-Chloro-2-phenyl-4-quinolinecarboxylic acid; 8-Chloro-2-phenylcinchoninic acid
EINECS	Contact for details

Quality Control

Our 8-Chloro-2-Phenylquinoline-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.