Description

5-(Bromomethyl)Benzo[D]Oxazole is a versatile brominated heterocyclic building block of significant interest in advanced organic synthesis. Its reactive bromomethyl group makes it a crucial intermediate for constructing complex molecular architectures through efficient cross-coupling and functionalization reactions. This compound is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new pesticides, herbicides, and fungicides, leveraging its reactivity to introduce the benzoxazole moiety.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes and tags for studying biological systems and mechanisms.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl and complex heterocyclic systems.
• Ligand and Catalyst Development: Useful for synthesizing novel chelating ligands and organocatalysts based on the benzoxazole scaffold.

Basic Information

Product Name	5-(Bromomethyl)Benzo[D]Oxazole
CAS No.	181038-98-2
Molecular Formula	C8H6BrNO
Molecular Weight	212.05 g/mol
Synonyms	5-(Bromomethyl)benzoxazole; 1,3-Benzoxazole, 5-(bromomethyl)-; 5-Bromomethylbenzoxazole; Benzo[d]oxazole, 5-(bromomethyl)-; 5-(Bromomethyl)-1,3-benzoxazole; 181038-98-2; Bromomethylbenzoxazole
EINECS	Contact for details

Quality Control

Our 5-(Bromomethyl)Benzo[D]Oxazole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to verify identity and purity against established specifications. Certificates of Analysis (COA) detailing all test results are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.