Description

(1R,3S)-Methyl 3-Aminocyclopentanecarboxylate Hydrochloride CAS NO 180196-56-9 is a high-purity chiral building block and pharmaceutical intermediate of significant synthetic utility. Its value lies in its defined stereochemistry, which is critical for the development of enantiomerically pure active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications in asymmetric synthesis and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Asymmetric Synthesis: Used as a building block to introduce the chiral 3-aminocyclopentane scaffold into more complex molecular architectures.
• Peptidomimetics Research: Serves as a constrained, cyclic amino acid analog in the design and development of peptide mimics.
• Agrochemical Synthesis: Employed in the research and production of enantiomerically pure pesticides and herbicides.
• Catalyst Ligand Preparation: A precursor for chiral ligands used in asymmetric catalysis.
• Academic & R&D: Utilized in university and corporate research laboratories for methodological studies in organic and medicinal chemistry.

Basic Information

Product Name	(1R,3S)-Methyl 3-Aminocyclopentanecarboxylate Hydrochloride
CAS No.	180196-56-9
Molecular Formula	C7H14ClNO2
Molecular Weight	179.65 g/mol
Synonyms	Methyl (1R,3S)-3-aminocyclopentanecarboxylate hydrochloride; (1R,3S)-3-Amino-1-cyclopentanecarboxylic acid methyl ester hydrochloride; Methyl (1R,3S)-3-aminocyclopentane-1-carboxylate HCl; (1R,3S)-3-Aminocyclopentanecarboxylic acid methyl ester hydrochloride; trans-Methyl 3-aminocyclopentanecarboxylate hydrochloride; (1R,3S)-Methyl 3-aminocyclopentane-1-carboxylate hydrochloride; Methyl 3-aminocyclopentanecarboxylate HCl (trans- isomer)
EINECS	Contact for details

Quality Control

Our (1R,3S)-Methyl 3-Aminocyclopentanecarboxylate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.