Description

(+)-2,2'-Methylenebis[(3Ar,8As)-3A,8A-Dihydro-8H-Indeno[1,2-D]Oxazole] is a high-purity, chiral bis-oxazoline ligand of significant interest in advanced chemical synthesis. This compound matters for its exceptional ability to induce stereoselectivity in catalytic reactions, enabling the production of enantiomerically pure intermediates and active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for developing novel, high-value chiral compounds.

Application

• Asymmetric Catalysis: A key chiral ligand for enantioselective transformations such as Diels-Alder, cyclopropanation, and aldol reactions.
• Pharmaceutical Intermediates: Critical for the synthesis of enantiomerically pure drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of chiral pesticides and herbicides with improved efficacy and environmental profiles.
• Fine Chemical Production: Enables the manufacture of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.
• Academic & Industrial Research: A valuable tool for methodological development in organic chemistry and process optimization.
• Material Science: Potential applications in the synthesis of chiral polymers and advanced functional materials.

Basic Information

Product Name	(+)-2,2'-Methylenebis[(3Ar,8As)-3A,8A-Dihydro-8H-Indeno[1,2-D]Oxazole]
CAS No.	180186-94-1
Molecular Formula	C23H20N2O2
Molecular Weight	356.42 g/mol
Synonyms	(+)-Methylene-bis-indenyl-oxazoline; (S,S)-Methylene-bis-indenyl-oxazoline; (S,S)-MBI; (S,S)-2,2'-Methylenebis(3a,8a-dihydro-8H-indeno[1,2-d]oxazole); Chiral Bis(oxazoline) Ligand; (S,S)-IndaBOX; (+)-Bis(oxazoline) Ligand; (S,S)-Methylenebis(indenyloxazoline)
EINECS	Contact for details

Quality Control

Our production of (+)-2,2'-Methylenebis[(3Ar,8As)-3A,8A-Dihydro-8H-Indeno[1,2-D]Oxazole] adheres to stringent quality protocols to ensure batch-to-batch consistency and high chiral purity. All materials undergo rigorous analytical testing, including chiral HPLC, NMR, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and related substances is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and chiral integrity. Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.