Description

Ethyl 2-(Chloromethyl)-3-Quinolinecarboxylate is a versatile quinoline derivative that serves as a crucial synthetic intermediate in advanced organic chemistry. Its molecular architecture, featuring both a reactive chloromethyl group and an ester functionality, makes it a valuable building block for constructing complex heterocyclic systems. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those with quinoline-based pharmacophores for applications in oncology, anti-infectives, and central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the development of new pesticides, herbicides, and fungicides, leveraging the quinoline scaffold for biological activity.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of advanced organic materials, such as ligands for catalysts or components for organic electronics.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Fine Chemical Production: Acts as a building block for the manufacture of specialty dyes, pigments, and complex fragrance molecules.

Basic Information

Product Name	Ethyl 2-(Chloromethyl)-3-Quinolinecarboxylate
CAS No.	180161-74-4
Molecular Formula	C₁₃H₁₂ClNO₂
Molecular Weight	249.69 g/mol
Synonyms	Ethyl 2-(chloromethyl)quinoline-3-carboxylate; 3-Quinolinecarboxylic acid, 2-(chloromethyl)-, ethyl ester; 2-(Chloromethyl)-3-quinolinecarboxylic acid ethyl ester; Ethyl 2-chloromethylquinoline-3-carboxylate; Quinoline-3-carboxylic acid, 2-(chloromethyl)-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-(Chloromethyl)-3-Quinolinecarboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly closed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.