Description

Methyl 2-Amino-3-Iodobenzoate is a high-purity iodinated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both an amino and an iodo substituent, makes it a versatile intermediate for constructing complex molecules, particularly in pharmaceutical research and development. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as cross-coupling reactions and heterocycle synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing complex benzo-fused heterocycles or requiring selective functionalization via the iodine moiety.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the iodobenzoate scaffold is incorporated.
• Material Science Research: Serves as a monomer or functionalization agent in the development of advanced organic materials, such as liquid crystals or organic semiconductors.
• Cross-Coupling Reactions: The iodine atom is highly reactive in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira, Heck) for carbon-carbon bond formation.
• Ligand and Catalyst Development: The amino and ester groups can be modified to create novel chelating ligands for metal catalysts.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized iodinated dyes and pigments.

Basic Information

Product Name	Methyl 2-Amino-3-Iodobenzoate
CAS No.	180161-60-8
Molecular Formula	C8H8INO2
Molecular Weight	277.06 g/mol
Synonyms	2-Amino-3-iodobenzoic acid methyl ester; Methyl 3-iodo-2-aminobenzoate; Benzoic acid, 2-amino-3-iodo-, methyl ester; 3-Iodoanthranilic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2-Amino-3-Iodobenzoate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research and scale-up processes. We provide comprehensive analytical data with each shipment. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request and are integral to our commitment to supply chain transparency and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is light-sensitive and should be handled and stored away from direct light exposure to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.