Description

tert-Butyl 6-Bromo-2,2,4-Trimethylquinoline-1(2H)-Carboxylate is a high-purity, protected quinoline derivative serving as a critical synthetic intermediate. Its value lies in providing a versatile and reactive scaffold for constructing complex molecules in advanced research and development. This compound is essential for pharmaceutical chemists and agrochemical researchers engaged in the synthesis of novel active ingredients, where precise molecular architecture is paramount.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the quinoline core's bioactivity.
• Organic Synthesis & Material Science: Serves as a precursor for creating functionalized heterocyclic compounds used in ligands, catalysts, and advanced organic materials.
• Academic & R&D Laboratories: Employed in methodological studies and as a standard reagent for exploring new coupling and cyclization reactions.

Basic Information

Product Name	tert-Butyl 6-Bromo-2,2,4-Trimethylquinoline-1(2H)-Carboxylate
CAS No.	179894-35-0
Molecular Formula	C₁₇H₂₀BrNO₂
Molecular Weight	350.25 g/mol
Synonyms	1,2-Dihydro-6-bromo-2,2,4-trimethylquinoline-1-carboxylic acid tert-butyl ester; 6-Bromo-2,2,4-trimethyl-1,2-dihydroquinoline-1-carboxylic acid tert-butyl ester; tert-Butyl 6-bromo-2,2,4-trimethyl-1,2-dihydroquinoline-1-carboxylate; 1-BOC-6-bromo-2,2,4-trimethyl-1,2-dihydroquinoline; BOC-6-Bromo-TMQ; 179894-35-0; 6-Bromo-2,2,4-trimethylquinoline N-BOC derivative
EINECS	Contact for details

Quality Control

Our production of tert-Butyl 6-Bromo-2,2,4-Trimethylquinoline-1(2H)-Carboxylate adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. All materials are characterized by modern analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is light-sensitive (store away from light). Keep container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.