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(R)-(+)-6,6'-Dibromo-2,2'-Bis(Methoxymethoxy)-1,1'-Binaphthyl CAS NO 179866-74-1


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CAS No.:179866-74-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(R)-(+)-6,6'-Dibromo-2,2'-Bis(Methoxymethoxy)-1,1'-Binaphthyl is a high-value, enantiomerically pure binaphthyl derivative that serves as a critical chiral building block and ligand precursor in advanced organic synthesis. Its core value lies in enabling the production of highly selective catalysts and optically active compounds, which are essential for modern pharmaceutical and fine chemical manufacturing. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials industries for applications in asymmetric catalysis and chiral resolution.

Application

  • Chiral Ligand Synthesis: A key intermediate for preparing sophisticated axially chiral phosphine and diamine ligands used in asymmetric hydrogenation and cross-coupling reactions.
  • Pharmaceutical Intermediates: Employed in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) for drugs targeting central nervous system disorders and cardiovascular diseases.
  • Asymmetric Catalyst Development: Serves as a foundational scaffold for developing novel organocatalysts and metal-complex catalysts with high enantioselectivity.
  • Material Science Research: Used in the creation of chiral polymers and liquid crystals for advanced optical and electronic materials.
  • Agrochemical Synthesis: A building block for producing chiral herbicides and fungicides with improved efficacy and environmental profiles.
  • Academic & Industrial R&D: A valuable tool compound for methodological studies in stereoselective synthesis and catalysis research.

Basic Information

Product Name (R)-(+)-6,6'-Dibromo-2,2'-Bis(Methoxymethoxy)-1,1'-Binaphthyl
CAS No. 179866-74-1
Molecular Formula C24H22Br2O4
Molecular Weight 534.24 g/mol
Synonyms (R)-6,6'-Dibromo-2,2'-bis(methoxymethoxy)-1,1'-binaphthalene; (R)-(+)-6,6'-Dibromo-BINOL MOM ether; (R)-6,6'-Dibromo-2,2'-bis(methoxymethoxy)-1,1'-binaphthyl; (R)-6,6'-Dibromo-2,2'-di(methoxymethoxy)-1,1'-binaphthyl; (R)-BINOL-6,6'-dibromo-2,2'-bis-MOM-ether; 1,1'-Binaphthalene-2,2'-diol, 6,6'-dibromo-2,2'-bis(methoxymethoxy)-, (1R)-; (R)-6,6'-Dibromobinaphthol MOM ether
EINECS Contact for details

Quality Control

Our (R)-(+)-6,6'-Dibromo-2,2'-Bis(Methoxymethoxy)-1,1'-Binaphthyl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure high chemical and optical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and chiral purity are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged use to maintain stability.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Enantiomeric Excess (Chiral HPLC) ≥ 99.0% ee
Melting Point Contact for details
Heavy Metals < 10 ppm
Residual Solvents (GC) Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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