Description

n-Boc-8-Amino-2-Methylquinoline CAS NO 179627-10-2 is a high-purity, protected amine derivative of 2-methylquinoline, serving as a critical building block in advanced organic synthesis. Its primary value lies in the Boc (tert-butoxycarbonyl) protecting group, which safeguards the amine functionality during complex multi-step reactions, enabling the precise construction of sophisticated molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those containing quinoline or fused heterocyclic scaffolds with therapeutic potential.
• Agrochemical Research: Used in the development of new pesticides, herbicides, and fungicides where the quinoline structure imparts specific biological activity.
• Organic Synthesis Building Block: Employed in medicinal chemistry for the construction of libraries of compounds via amide coupling, reductive amination, and other transformations after deprotection.
• Material Science Precursor: Can be utilized in the synthesis of organic ligands for catalysis or functional molecules for advanced materials.
• Academic & R&D: Serves as a valuable reagent in university and corporate research laboratories for methodological development and exploratory synthesis.

Basic Information

Item	Details
Product Name	n-Boc-8-Amino-2-Methylquinoline
CAS No.	179627-10-2
Molecular Formula	C₁₅H₁₈N₂O₂
Molecular Weight	258.32 g/mol
Synonyms	tert-Butyl 8-amino-2-methylquinoline-1(2H)-carboxylate; 8-[(tert-Butoxycarbonyl)amino]-2-methylquinoline; 1,1-Dimethylethyl 8-amino-2-methyl-1,2-dihydroquinoline-1-carboxylate; 8-(Boc-amino)-2-methylquinoline; Boc-8-Amino-2-Me-quinoline; N-Boc-8-Amino-2-methylquinoline; 8-Amino-2-methylquinoline N-Boc derivative
EINECS	Contact for details

Quality Control

Our n-Boc-8-Amino-2-Methylquinoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high chemical purity and identity confirmation, meeting the stringent requirements for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), identity (IR, NMR), and impurity profiles is provided with each shipment to guarantee batch-to-batch consistency and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.