Description

3-Azabicyclo[3.1.0]Hexane-6-Carboxylicacid,Ethylester(9Ci) is a high-value, bicyclic organic compound featuring a fused cyclopropane and pyrrolidine ring system, serving as a critical synthetic intermediate. This structurally constrained scaffold is prized for its ability to impart rigidity and unique three-dimensional geometry to target molecules, which is essential for modulating biological activity and physical properties. It is primarily sought by pharmaceutical and agrochemical R&D organizations for the synthesis of novel active ingredients, including potential central nervous system (CNS) agents and enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting neurological disorders and other therapeutic areas requiring conformationally restricted motifs.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the bicyclic structure can contribute to enhanced binding affinity and environmental stability.
• Chemical Biology & Proteomics: Employed as a scaffold or linker in the design of chemical probes and activity-based protein profiling (ABPP) agents to study enzyme function.
• Material Science Precursor: Acts as a specialized monomer or precursor for advanced polymers and functional materials with tailored properties.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploring new chemical spaces in organic synthesis.

Basic Information

Product Name	3-Azabicyclo[3.1.0]Hexane-6-Carboxylicacid,Ethylester(9Ci)
CAS No.	179236-79-4
Molecular Formula	C8H13NO2
Molecular Weight	155.19 g/mol
Synonyms	Ethyl 3-azabicyclo[3.1.0]hexane-6-carboxylate; 6-Carbethoxy-3-azabicyclo[3.1.0]hexane; 3-Azabicyclo[3.1.0]hexane-6-carboxylic acid ethyl ester; 1-Aza-4-ethyl bicyclo[3.1.0]hexane-6-carboxylate; Ethyl 1-azabicyclo[3.1.0]hexane-6-carboxylate (related isomer); ABN-hexane-6-COOEt; Bicyclic proline derivative ethyl ester
EINECS	Contact for details

Quality Control

Our production of 3-Azabicyclo[3.1.0]Hexane-6-Carboxylicacid,Ethylester(9Ci) adheres to stringent quality protocols suitable for advanced R&D and pre-clinical applications. Every batch is characterized and tested to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing comprehensive analytical results are provided with each shipment. We support development projects with custom synthesis and purity grades upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.