Description

Altinicline is a high-purity, synthetic chemical compound with significant research and development applications. This compound is valued for its specific pharmacological activity as a potent and selective agonist at neuronal nicotinic acetylcholine receptors (nAChRs). It serves as a critical research-grade intermediate and reference standard for pharmaceutical development, particularly in neuroscience and drug discovery programs targeting neurological disorders.

Application

• Pharmaceutical Research & Development: As a key reference standard and pharmacological tool in the study of neuronal nicotinic acetylcholine receptors (nAChRs).
• Neuroscience Studies: Used in preclinical research to investigate receptor function, signaling pathways, and potential therapeutic applications for cognitive and neurological conditions.
• Drug Discovery Intermediary: Serves as a critical synthetic intermediate or lead compound in the development of novel therapeutics targeting the central nervous system.
• Biochemical Assay Development: Employed in high-throughput screening (HTS) and in vitro assays to identify and characterize new drug candidates.
• Academic & Institutional Research: Supplied to universities and research institutes for fundamental studies in neuropharmacology and medicinal chemistry.

Basic Information

Product Name	Altinicline
CAS No.	179120-51-5
Molecular Formula	C11H13N3O
Molecular Weight	203.24 g/mol
Synonyms	5-Ethynyl-1,4-diazabicyclo[3.2.2]nonan-3-one; Altiniklin; Altinikline; (R)-5-Ethynyl-1-azabicyclo[2.2.2]octan-3-one oxime; GTS-21; DMXBA; 3-[(2R)-1-Azabicyclo[2.2.2]oct-2-yl]-5-ethynylpyridin-2-ol
EINECS	Contact for details

Quality Control

Our Altinicline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for research chemicals, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.