Description

4-Chloro-6-Fluoro- Quinoline-3-Carboxylic Acid is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its versatile quinoline scaffold, which is strategically functionalized with chlorine and fluorine atoms to enable precise molecular modifications. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting infectious diseases and central nervous system disorders.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the quinoline core.
• Material Science: Serves as a building block for creating functional organic materials, such as ligands for catalysts and components for organic electronics.
• Chemical Synthesis: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization due to its modifiable carboxylic acid group.
• Academic & Contract Research: Essential for fundamental research in heterocyclic chemistry and for contract research organizations (CROs) developing custom synthesis routes.

Basic Information

Product Name	4-Chloro-6-Fluoro- Quinoline-3-Carboxylic Acid
CAS No.	179024-67-0
Molecular Formula	C10H5ClFNO2
Molecular Weight	225.60 g/mol
Synonyms	4-Chloro-6-fluoroquinoline-3-carboxylic acid; 3-Quinolinecarboxylic acid, 4-chloro-6-fluoro-; 4-Chloro-6-fluoro-3-quinolinecarboxylic acid; 6-Fluoro-4-chloroquinoline-3-carboxylic acid; 4-Chloro-6-fluoroquinoline-3-carboxylate; 179024-67-0; Quinoline-3-carboxylic acid, 4-chloro-6-fluoro-
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-Fluoro- Quinoline-3-Carboxylic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support compliance with relevant regulatory frameworks for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.