Description

4(1H)-Quinazolinone, 2-(5-Amino-2-Propoxyphenyl)-8-Methoxy- (9Ci) is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular design. It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of investigational drug candidates, particularly those targeting specific enzyme pathways.
• Drug Discovery & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization in research laboratories.
• Chemical Synthesis: Serves as a versatile scaffold for constructing more complex heterocyclic compounds in organic synthesis.
• Biochemical Research: Employed as a reference standard or tool compound in biochemical assays and pharmacological studies.
• API Manufacturing: Integrated into the production process of specialized active pharmaceutical ingredients under controlled GMP environments.

Basic Information

Product Name	4(1H)-Quinazolinone, 2-(5-Amino-2-Propoxyphenyl)-8-Methoxy- (9Ci)
CAS No.	178937-98-9
Molecular Formula	C18H19N3O3
Molecular Weight	325.36 g/mol
Synonyms	2-(5-Amino-2-propoxyphenyl)-8-methoxy-4(1H)-quinazolinone; 8-Methoxy-2-[5-amino-2-(propoxy)phenyl]-4(1H)-quinazolinone; 2-(5-Amino-2-propoxy-phenyl)-8-methoxy-1H-quinazolin-4-one; Quinazolin-4(1H)-one, 2-(5-amino-2-propoxyphenyl)-8-methoxy-; 178937-98-9
EINECS	Contact for details

Quality Control

Our 4(1H)-Quinazolinone derivative is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support development and commercial projects requiring material that meets stringent ICH guidelines for impurities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.