Description

3-Chloro-5-Fluoro-Benzo[D]Isoxazole is a high-purity, heterocyclic aromatic compound serving as a critical building block in advanced organic synthesis. Its unique halogenated isoxazole structure makes it an invaluable intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for creating new molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the halogenated benzoisoxazole moiety contributes to biological efficacy.
• Material Science Research: Serves as a precursor for synthesizing novel organic electronic materials, ligands for catalysis, and functional dyes.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules under cGMP conditions where applicable.

Basic Information

Product Name	3-Chloro-5-Fluoro-Benzo[D]Isoxazole
CAS No.	178747-50-7
Molecular Formula	C7H3ClFNO
Molecular Weight	171.56 g/mol
Synonyms	3-Chloro-5-fluorobenzo[d]isoxazole; 3-Chloro-5-fluoro-1,2-benzisoxazole; 5-Fluoro-3-chlorobenzo[d]isoxazole; 5-Fluoro-3-chloro-1,2-benzisoxazole; 1,2-Benzisoxazole, 3-chloro-5-fluoro-; 178747-50-7; 3-Cl-5-F-Benzoisoxazole
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-Fluoro-Benzo[D]Isoxazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring reliable and consistent raw material specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.