Description

Rel-(8R,8'R)-Dimethyl-(7S,7'R)-Bis(3,4-Methylenedioxyphenyl)Tetrahydro-Furan is a high-purity, stereochemically defined synthetic intermediate of significant interest in advanced organic synthesis. Its complex, chiral structure makes it a valuable building block for the development of novel, optically active compounds. This product is essential for research and development chemists in the pharmaceutical and fine chemical industries seeking to create sophisticated molecular architectures with specific biological activities.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of potential active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) targets.
• Asymmetric Synthesis: Utilized as a sophisticated ligand or building block in catalytic asymmetric reactions to induce high enantioselectivity.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and the construction of complex natural product analogs or novel chemical entities.
• Fine Chemical Production: Used in the multi-step synthesis of specialty chemicals, flavors, fragrances, and advanced materials requiring precise stereochemical control.
• Academic & Industrial R&D: A critical tool for chemists in universities and corporate labs exploring new synthetic methodologies and complex molecule construction.

Basic Information

Product Name	Rel-(8R,8'R)-Dimethyl-(7S,7'R)-Bis(3,4-Methylenedioxyphenyl)Tetrahydro-Furan
CAS No.	178740-32-4
Molecular Formula	C22H22O6
Molecular Weight	382.41 g/mol
Synonyms	(7S,7'R,8R,8'R)-Dimethyl-7,7'-bis(3,4-methylenedioxyphenyl)tetrahydrofuran; (7S,7'R,8R,8'R)-Dimethyl-7,7'-bis(benzo[d][1,3]dioxol-5-yl)tetrahydrofuran; Rel-(+)-Galbelgin; (+)-Galbelgin; Galbelgin (rel form); Tetrahydrofuran lignan derivative; Dimethyl bis(methylenedioxyphenyl)tetrahydrofuran
EINECS	Contact for details

Quality Control

Every batch of Rel-(8R,8'R)-Dimethyl-(7S,7'R)-Bis(3,4-Methylenedioxyphenyl)Tetrahydro-Furan is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and stereochemical purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de (diastereomeric excess)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.