Description

(2R,3R,4S,5R,6R)-2-Dimethylamino-6-(Hydroxymethyl)Oxane-3,4,5-Triol Hydrochloride is a high-purity, stereochemically defined carbohydrate derivative, serving as a critical chiral building block and reference standard in advanced synthesis. Its value lies in providing a consistent and reliable source of a specific amino sugar hydrochloride salt, essential for research and development where stereochemical integrity is paramount. This compound is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions engaged in glycoscience, antiviral research, and the development of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel glycosidase inhibitors, antiviral agents, and complex carbohydrate-based therapeutics.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to carbohydrate metabolism and processing.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Glycochemistry & Glycobiology: A fundamental building block for constructing oligosaccharides, glycoconjugates, and glycomimetics for structure-activity relationship studies.
• Process Development: Employed in scaling up synthetic routes for active pharmaceutical ingredients (APIs) that require this specific stereoisomer.
• Academic Synthesis: Used in teaching and research laboratories to demonstrate advanced synthetic methodologies in carbohydrate chemistry.

Basic Information

Item	Details
Product Name	(2R,3R,4S,5R,6R)-2-Dimethylamino-6-(Hydroxymethyl)Oxane-3,4,5-Triol Hydrochloride
CAS No.	178563-31-0
Molecular Formula	C9H20ClNO6
Molecular Weight	273.71 g/mol
Synonyms	2-Deoxy-2-(dimethylamino)-D-glucopyranose Hydrochloride; D-Glucosamine, N,N-dimethyl-, hydrochloride (2R,3R,4S,5R,6R)-; N,N-Dimethyl-D-glucosamine Hydrochloride; (2R,3R,4S,5R,6R)-2-(Dimethylamino)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol hydrochloride; 2-Amino-2-deoxy-D-glucose, N,N-dimethyl-, hydrochloride; N,N-Dimethylglucosamine HCl; Amino sugar hydrochloride derivative
EINECS	Contact for details

Quality Control

Every batch of (2R,3R,4S,5R,6R)-2-Dimethylamino-6-(Hydroxymethyl)Oxane-3,4,5-Triol Hydrochloride is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and stereochemical integrity. Our quality assurance protocols are designed to meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), chiral purity, water content, and residual solvents is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation by atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.