Description

6-Bromo-4-Phenylquinolin-2(1H)-One is a high-purity, synthetically valuable quinoline derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in its functionalized heterocyclic structure, which provides a versatile scaffold for constructing complex molecules in pharmaceutical and materials research. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition or other biological pathways where the quinoline core is pharmacologically active.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its halogenated aromatic system for bioactivity.
• Organic Light-Emitting Diodes (OLEDs): Serves as a starting material for synthesizing electron-transport or host materials in OLED devices due to its rigid, conjugated structure.
• Ligand Synthesis: Utilized in the preparation of nitrogen-containing ligands for catalysis and coordination chemistry.
• Chemical Biology Probes: Acts as a scaffold for developing fluorescent probes or photoaffinity labels for studying biological systems.
• Academic & Contract Research: Employed in universities and CROs for methodological studies in heterocyclic chemistry and cross-coupling reactions.

Basic Information

Product Name	6-Bromo-4-Phenylquinolin-2(1H)-One
CAS No.	178490-58-9
Molecular Formula	C₁₅H₁₀BrNO
Molecular Weight	300.15 g/mol
Synonyms	6-Bromo-4-phenyl-1,2-dihydroquinolin-2-one; 6-Bromo-4-phenyl-2(1H)-quinolinone; 2(1H)-Quinolinone, 6-bromo-4-phenyl-; 4-Phenyl-6-bromoquinolin-2(1H)-one; 6-Bromo-4-phenylquinolin-2-ol (tautomer); 6-Bromo-4-phenyl-2-hydroxyquinoline; 6-Bromo-4-phenyl-2-quinolinol
EINECS	Contact for details

Quality Control

Our 6-Bromo-4-Phenylquinolin-2(1H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The compound should be kept under an inert atmosphere for long-term storage to ensure stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.