Description

3-Quinolinecarboxylic Acid, 7-[(2-Aminoethyl)Amino]-1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-Oxo- is a high-purity, advanced pharmaceutical intermediate of significant commercial importance. This compound serves as a critical building block in the synthesis of novel fluoroquinolone antibiotics, offering a pathway to enhanced therapeutic agents. It is essential for research and development chemists, process development scientists, and manufacturers in the global pharmaceutical and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of next-generation fluoroquinolone antibacterial agents.
• Active Pharmaceutical Ingredient (API) Development: Used in research for developing new antibiotic compounds with improved efficacy and spectrum of activity.
• Chemical Synthesis Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies.
• Process Chemistry: Employed in the scale-up and optimization of manufacturing routes for complex drug molecules.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and regulatory submissions.

Basic Information

Product Name	3-Quinolinecarboxylic Acid, 7-[(2-Aminoethyl)Amino]-1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-Oxo-
CAS No.	178489-07-1
Molecular Formula	C₁₅H₁₇FN₄O₃
Molecular Weight	320.32 g/mol
Synonyms	1-Cyclopropyl-7-[(2-aminoethyl)amino]-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid; 7-[(2-Aminoethyl)Amino]-1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-Oxo-3-Quinolinecarboxylic Acid; 1-Cyclopropyl-6-fluoro-1,4-dihydro-7-[(2-aminoethyl)amino]-4-oxo-3-quinolinecarboxylic acid; Intermediate for Garenoxacin; Garenoxacin Intermediate; T-3811 Intermediate; OPC-17116 Intermediate; BMS-284756 Intermediate
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid, 7-[(2-Aminoethyl)Amino]-1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-Oxo- is manufactured under strict quality management systems. The product undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet GMP, ICH Q7, or other relevant pharmaceutical guidelines upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.