Description

3-Quinolinecarboxylic Acid, 7-Chloro-1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-Oxo- is a high-purity pharmaceutical intermediate of significant commercial importance. This compound is valued for its role as a critical building block in the synthesis of advanced active pharmaceutical ingredients (APIs). It is primarily sought by manufacturers in the pharmaceutical and fine chemical industries for research and production applications.

Application

This advanced intermediate is designed for specialized synthesis applications, particularly in the development of modern therapeutics.

• Key Intermediate for Fluoroquinolone Antibiotics: Serves as a crucial precursor in the synthesis of next-generation broad-spectrum antibacterial agents.
• Pharmaceutical Research & Development (R&D): Used in medicinal chemistry for the discovery and optimization of new drug candidates with improved efficacy.
• Active Pharmaceutical Ingredient (API) Manufacturing: Incorporated into scaled-up production processes for final drug substances under controlled GMP environments.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for complex, high-value organic molecules.
• Reference Standard: Utilized as an analytical standard for quality control and regulatory compliance testing in pharmaceutical labs.

Basic Information

Product Name	3-Quinolinecarboxylic Acid, 7-Chloro-1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-Oxo-
CAS No.	178489-04-8
Molecular Formula	C13H9ClFNO3
Molecular Weight	281.67 g/mol
Synonyms	7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid; 1-Cyclopropyl-7-chloro-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid; Gatifloxacin Intermediate; AM-1155 Intermediate; (±)-1-Cyclopropyl-6-fluoro-1,4-dihydro-7-chloro-8-methoxy-4-oxo-3-quinolinecarboxylic Acid (related); 3-Quinolinecarboxylic acid, 1,4-dihydro-7-chloro-1-cyclopropyl-6-fluoro-4-oxo-; GTFX Intermediate
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid, 7-Chloro-1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-Oxo- is produced under stringent quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are available upon request, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.