Description

1-Chloro-3-Chloromethyl-5-Methoxy-Benzene is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its bifunctional nature, featuring both a chloro and a reactive chloromethyl group on a methoxy-substituted benzene ring, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for molecules requiring a substituted benzyl chloride moiety.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides where its aromatic core serves as a foundational structure.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for metal-catalyzed coupling reactions and other catalytic processes.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials.
• Fine Chemical Production: Utilized in custom synthesis and the manufacture of dyes, pigments, and other performance chemicals.

Basic Information

Product Name	1-Chloro-3-Chloromethyl-5-Methoxy-Benzene
CAS No.	178486-30-1
Molecular Formula	C8H8Cl2O
Molecular Weight	191.05 g/mol
Synonyms	3-Chloromethyl-5-chloroanisole; 5-Chloro-3-(chloromethyl)anisole; 1-Chloro-3-(chloromethyl)-5-methoxybenzene; 3-Chloro-5-methoxybenzyl chloride; 5-Methoxy-3-chlorobenzyl chloride; Benzene, 1-chloro-3-(chloromethyl)-5-methoxy-; (3-Chloro-5-methoxyphenyl)methyl chloride
EINECS	Contact for details

Quality Control

Our 1-Chloro-3-Chloromethyl-5-Methoxy-Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to the reactive chloromethyl group, it should be stored separately from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.