Description

5-(tert-Butoxycarbonylamino)Isophthalic Acid is a high-purity, protected amino acid derivative widely used as a key building block in organic synthesis. Its primary value lies in the tert-butoxycarbonyl (Boc) protecting group, which safeguards the amine functionality during complex multi-step reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and advanced materials sectors who require reliable, high-quality intermediates for peptide synthesis and the development of novel polymers and metal-organic frameworks.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex peptide-based active pharmaceutical ingredients (APIs) and drug candidates.
• Peptide Synthesis: Serves as a protected amino acid building block in solid-phase and solution-phase peptide synthesis for research and production.
• Polymer Chemistry: Used to introduce functional, aromatic dicarboxylic acid units into specialty polymers, influencing thermal and mechanical properties.
• Ligand Synthesis: Acts as a starting material for creating sophisticated chelating ligands used in catalysis and material science.
• Metal-Organic Frameworks (MOFs): Employed as an organic linker in the construction of novel MOFs for gas storage, separation, and catalysis.
• Chemical Research: A valuable reagent for academic and industrial R&D in medicinal chemistry and supramolecular chemistry.

Basic Information

Product Name	5-(tert-Butoxycarbonylamino)Isophthalic Acid
CAS No.	178446-63-4
Molecular Formula	C13H15NO6
Molecular Weight	281.26 g/mol
Synonyms	5-[(tert-Butoxycarbonyl)amino]isophthalic acid; 5-(Boc-amino)isophthalic acid; 1,3-Benzenedicarboxylic acid, 5-[[(1,1-dimethylethoxy)carbonyl]amino]-; 5-Aminoisophthalic acid N-Boc derivative; Boc-5-aminoisophthalic acid; 5-(N-Boc-amino)isophthalic acid; tert-Butyl (3,5-dicarboxyphenyl)carbamate
EINECS	Contact for details

Quality Control

Our 5-(tert-Butoxycarbonylamino)Isophthalic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical and research applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.