Description

3-Isothiazolecarboxylicacid,4-Hydroxy-(9Ci) is a specialized heterocyclic carboxylic acid derivative that serves as a valuable synthetic intermediate. Its unique isothiazole core functionalized with both carboxylic acid and hydroxyl groups makes it a versatile building block for pharmaceutical and agrochemical research. This compound is primarily sought after by R&D chemists and process development scientists in the fine chemical and life sciences industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting infectious diseases or central nervous system disorders.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging the bioactivity of the isothiazole moiety.
• Ligand Synthesis: Serves as a precursor for creating complexing agents or chelating ligands in coordination chemistry and catalysis.
• Material Science: Potential monomer or functionalization agent for creating polymers with specific electronic or adhesive properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzymatic activity or cellular processes.

Basic Information

Product Name	3-Isothiazolecarboxylicacid,4-Hydroxy-(9Ci)
CAS No.	178316-76-2
Molecular Formula	C4H3NO3S
Molecular Weight	145.14 g/mol
Synonyms	4-Hydroxy-1,2-thiazole-3-carboxylic acid; 4-Hydroxyisothiazole-3-carboxylic acid; 3-Carboxy-4-hydroxyisothiazole; 4-Hydroxy-3-isothiazolecarboxylic acid; 4-Hydroxyisothiazole-3-carboxylate; 1,2-Thiazole-3-carboxylic acid, 4-hydroxy-; 4-Hydroxy-1,2-thiazole-3-carboxylate
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for all our fine chemical intermediates. Production follows current Good Manufacturing Practices (cGMP) where applicable, and each batch is analyzed to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing specifications such as assay (HPLC), identity (IR, NMR), and impurity profiles. Our quality system is designed to meet the exacting standards of pharmaceutical and advanced R&D customers.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider the use of a desiccant.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.