Description

2-Chloro-5,6,7,8-Tetrahydro-4(3H)-Quinazolinone is a versatile heterocyclic building block of significant interest in advanced organic synthesis. Its core quinazolinone scaffold, functionalized with a chlorine atom, makes it a critical intermediate for the development of novel pharmacologically active compounds. This high-purity intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to create new molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Chemical Biology Probe Synthesis: Employed in constructing molecular probes for studying enzyme function and biological pathways in academic and industrial research settings.
• Material Science Precursor: Acts as a building block for creating specialized organic compounds used in advanced materials, such as ligands for catalysts or components in organic electronics.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and non-commercial research quantities.

Basic Information

Product Name	2-Chloro-5,6,7,8-Tetrahydro-4(3H)-Quinazolinone
CAS No.	178308-51-5
Molecular Formula	C8H9ClN2O
Molecular Weight	184.62 g/mol
Synonyms	2-Chloro-4,5,6,7-tetrahydro-3H-quinazolin-4-one; 2-Chloro-5,6,7,8-tetrahydroquinazolin-4(3H)-one; 2-Chloro-4-oxo-1,4,5,6,7,8-hexahydroquinazoline; 4(3H)-Quinazolinone, 2-chloro-5,6,7,8-tetrahydro-; 2-Chloro-1,2,3,4-tetrahydroquinazolin-4-one
EINECS	Contact for details

Quality Control

Our 2-Chloro-5,6,7,8-Tetrahydro-4(3H)-Quinazolinone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.