Description

Benzenepropanoic Acid, A-Hydroxy-B-Methoxy-B-Phenyl-, (As)- is a high-purity chiral intermediate of significant importance in advanced organic synthesis. This compound is valued for its defined stereochemistry and functional groups, which are critical for constructing complex molecular architectures. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Used as a precursor or catalyst ligand in stereoselective chemical reactions to produce enantiomerically pure compounds.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, agrochemicals, and performance materials requiring specific stereochemistry.
• Academic & Industrial Research: Serves as a standard or starting material in methodological development and process chemistry research.
• Peptidomimetics & Bioactive Molecule Synthesis: Utilized in constructing non-natural amino acid derivatives and other bioactive scaffolds.

Basic Information

Product Name	Benzenepropanoic Acid, A-Hydroxy-B-Methoxy-B-Phenyl-, (As)-
CAS No.	178306-52-0
Molecular Formula	C16H16O4
Molecular Weight	272.30 g/mol
Synonyms	(2S)-2-Hydroxy-3-methoxy-3-phenylpropanoic acid; (S)-2-Hydroxy-3-methoxy-3-phenylpropionic acid; (S)-α-Hydroxy-β-methoxy-β-phenylpropionic acid; (S)-HMPPA; (S)-O-Methylmandelylglycolic acid; Benzenepropanoic acid, α-hydroxy-β-methoxy-β-phenyl-, (αS)-; L-HMPPA
EINECS	Contact for details

Quality Control

Our Benzenepropanoic Acid, A-Hydroxy-B-Methoxy-B-Phenyl-, (As)- is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) and chemical purity determination by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and fine chemical synthesis. Certificates of Analysis (COA) with full specification data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.