Description

1-(4-Azidophenyl)-2-(Fluoro-(18)F)Ethanone is a specialized fluorine-18 labeled radiopharmaceutical precursor, a critical building block for Positron Emission Tomography (PET) tracer synthesis. This compound matters because it enables the efficient, site-specific introduction of the positron-emitting isotope Fluorine-18 into complex molecules, which is essential for developing novel diagnostic imaging agents. Pharmaceutical researchers, radiochemists, and CDMOs in the nuclear medicine sector need this high-purity intermediate to create targeted PET tracers for oncology, neurology, and cardiology research.

Application

• PET Tracer Precursor: Primary building block for synthesizing Fluorine-18 labeled radiopharmaceuticals for diagnostic imaging.
• Oncology Research: Used to develop novel PET tracers for cancer detection, staging, and monitoring treatment efficacy.
• Neurological Disorder Imaging: Key intermediate in creating tracers targeting biomarkers associated with Alzheimer's, Parkinson's, and other CNS diseases.
• Cardiovascular Imaging Agent Synthesis: Facilitates the production of PET tracers for assessing myocardial perfusion and viability.
• Radiochemistry & Drug Discovery: Serves as a versatile reagent in research labs and CDMOs for developing and scaling new PET probes.
• GMP Manufacturing: Suitable for use in Good Manufacturing Practice (GMP) environments for the production of clinical-grade radiopharmaceuticals.

Basic Information

Product Name	1-(4-Azidophenyl)-2-(Fluoro-(18)F)Ethanone
CAS No.	178273-73-9
Molecular Formula	C8H6FN3O
Molecular Weight	179.15 g/mol
Synonyms	4-Azido-[18F]fluorobenzyl ketone; [18F]FBAz; 1-(4-Azidophenyl)-2-([18F]fluoro)ethan-1-one; 4-Azidophenacyl-[18F]fluoride; Fluorine-18 labeled azidophenacyl fluoride; PET precursor 178273-73-9; 18F-labeled azido precursor; Azidophenyl fluoroethanone (18F)
EINECS	Contact for details

Quality Control

Every batch of 1-(4-Azidophenyl)-2-(Fluoro-(18)F)Ethanone is manufactured and controlled under a strict quality management system. We provide comprehensive analytical data to support its use in research and GMP-compliant environments. Key parameters including radiochemical purity, specific activity, and chemical purity are verified via validated methods such as radio-HPLC and radio-TLC. A Certificate of Analysis (COA) detailing batch-specific results, including radionuclidic identity and purity, is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. Due to its light-sensitive and highly volatile nature, this material should be handled in appropriate containment and used promptly after receipt to ensure optimal performance. Follow all applicable radiation safety and laboratory guidelines.

Specification

Item	Specification
Appearance	Clear colorless to pale yellow solution
Identification (HPLC)	Conforms to reference standard
Radiochemical Purity (RCP)	≥ 95%
Chemical Purity (HPLC)	≥ 98%
Specific Activity	> 37 GBq/μmol at EOS
Radionuclidic Purity	≥ 99.9%
Solvent	Anhydrous Acetonitrile or specified
pH	6.0 - 8.0

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.