Description

1-(Methylsulfonyl)Spiro[Indoline-3,4'-Piperidine] is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic structure. This compound is of significant value in modern medicinal chemistry for its role as a key building block in the synthesis of novel, biologically active molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within the fields of central nervous system (CNS) and oncology drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a critical scaffold in the synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization programs.
• CNS Drug Development: A key precursor for compounds being investigated for neurological and psychiatric disorders.
• Oncology Research: Employed in the creation of novel small-molecule inhibitors for cancer therapy.
• Chemical Biology Probes: Utilized to develop tool compounds for studying biological mechanisms and target validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	1-(Methylsulfonyl)Spiro[Indoline-3,4'-Piperidine]
CAS No.	178261-41-1
Molecular Formula	C14H18N2O2S
Molecular Weight	278.37 g/mol
Synonyms	1-(Methanesulfonyl)spiro[indoline-3,4'-piperidine]; Spiro[indoline-3,4'-piperidine], 1-(methylsulfonyl)-; 1-Methylsulfonylspiro(indoline-3,4'-piperidine); 1-(Methylsulfonyl)spiro(indoline-3,4'-piperidine); 178261-41-1; 1-(Methanesulfonyl)-1,3-dihydrospiro[indole-3,4'-piperidine]; 1-(Methylsulfonyl)-1,3-dihydrospiro[indole-3,4'-piperidine]; 1-(Methylsulfonyl)spiro[indole-3,4'-piperidine]
EINECS	Contact for details

Quality Control

Our 1-(Methylsulfonyl)Spiro[Indoline-3,4'-Piperidine] is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis, to ensure it meets the exacting standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.