Description

3-Isoxazoleacetic Acid, 5-Hydroxy- (9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique isoxazole-acetic acid scaffold offers valuable functionalization points. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries for creating new molecular entities with targeted biological activity.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Fine Chemical Synthesis: Serves as a versatile precursor for creating complex molecules in custom synthesis and process development for specialty chemicals.
• Bioconjugation & Probe Development: The carboxylic acid functionality enables its use in bioconjugation chemistry for creating labeled probes or modifying biomolecules in life science research.
• Material Science Research: Potential monomer or additive in the development of specialized polymers with unique properties derived from the isoxazole ring.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for fundamental research in heterocyclic chemistry and methodology development.

Basic Information

Product Name	3-Isoxazoleacetic Acid, 5-Hydroxy- (9Ci)
CAS No.	178168-21-3
Molecular Formula	C5H5NO4
Molecular Weight	143.10 g/mol
Synonyms	5-Hydroxyisoxazole-3-acetic acid; 5-Hydroxy-1,2-oxazole-3-acetic acid; 3-Carboxymethyl-5-hydroxyisoxazole; 5-Hydroxy-3-isoxazoleacetic Acid; 5-Hydroxyisoxazol-3-ylacetic Acid; 3-Isoxazoleacetic acid, 5-hydroxy-; (5-Hydroxy-1,2-oxazol-3-yl)acetic acid
EINECS	Contact for details

Quality Control

Our 3-Isoxazoleacetic Acid, 5-Hydroxy- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.