Description

Br-PEG7-Br is a bifunctional polyethylene glycol (PEG) derivative featuring bromine end groups, serving as a versatile heterobifunctional linker. This compound is crucial for introducing PEG spacers into molecules, enhancing solubility, reducing immunogenicity, and improving pharmacokinetic properties. It is primarily utilized by researchers and manufacturers in the pharmaceutical, bioconjugation, and materials science sectors for drug delivery system development, polymer synthesis, and surface modification.

Application

• Pharmaceutical Linker: A key intermediate for creating PEGylated drugs, prodrugs, and antibody-drug conjugates (ADCs) to improve therapeutic efficacy and stability.
• Polymer Chemistry: Acts as a chain extender or cross-linking agent in the synthesis of functional polymers, hydrogels, and block copolymers.
• Surface Functionalization: Used to modify nanoparticles, quantum dots, or solid surfaces with PEG brushes to create stealth coatings or reactive platforms.
• Bioconjugation: Facilitates the attachment of biomolecules (peptides, proteins, oligonucleotides) to other entities via the reactive bromine termini.
• Materials Science: Employed in developing advanced materials with tailored properties for biomedical and nanotechnology applications.
• Research & Development: Serves as a valuable tool compound in organic synthesis and medicinal chemistry for exploring new chemical entities.

Basic Information

Product Name	Br-PEG7-Br
CAS No.	177987-04-1
Molecular Formula	C16H32Br2O7
Molecular Weight	496.23 g/mol
Synonyms	1,11-Dibromo-3,6,9-trioxaundecane; α,ω-Dibromo-hepta(ethylene glycol); Bis(2-bromoethyl) ether of tetraethylene glycol; PEG-7 dibromide; Heptaethylene glycol dibromide; 2,2'-(Ethane-1,2-diylbis(oxy))bis(ethane-2,1-diyl) bis(2-bromoacetate) (related ester form); Br-(CH2CH2O)7-CH2CH2-Br
EINECS	Contact for details

Quality Control

Our Br-PEG7-Br is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets high-purity standards suitable for research and commercial applications. Certificates of Analysis (COA) documenting identity, purity, and critical specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Molecular Weight (GPC)	Consistent with theoretical value

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.