Description

(R)-3-Amino-4-(4-Methylphenyl)Butanoic Acid Hydrochloride is a chiral, non-proteinogenic amino acid derivative of significant synthetic utility. This compound serves as a crucial pharmaceutical intermediate and a versatile building block in asymmetric synthesis. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and fine chemical sectors for the synthesis of active pharmaceutical ingredients (APIs), chiral ligands, and complex organic molecules.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and metabolic disorder drug candidates.
• Asymmetric Synthesis: Serves as a valuable building block for constructing complex, enantiomerically pure molecules in medicinal chemistry and total synthesis projects.
• Peptidomimetics Research: Used in the design and synthesis of peptide analogs and mimetics to modulate biological activity and improve metabolic stability.
• Chiral Catalyst & Ligand Preparation: A precursor for developing novel chiral auxiliaries, catalysts, and ligands used in enantioselective transformations.
• Agrochemical Synthesis: Intermediate in the production of chiral active ingredients for crop protection products.
• Academic & Industrial R&D: Essential for chemical biology studies, method development in organic synthesis, and process chemistry optimization.

Basic Information

Product Name	(R)-3-Amino-4-(4-Methylphenyl)Butanoic Acid Hydrochloride
CAS No.	177839-85-9
Molecular Formula	C11H16ClNO2
Molecular Weight	229.70 g/mol
Synonyms	(R)-3-Amino-4-(p-tolyl)butanoic acid hydrochloride; (R)-3-Amino-4-(4-methylphenyl)butyric acid hydrochloride; (3R)-3-Amino-4-(4-methylphenyl)butanoic acid hydrochloride; D-3-Amino-4-(4-methylphenyl)butanoic acid hydrochloride; (R)-β-Amino-4-methylbenzenebutanoic acid hydrochloride; (R)-3-Amino-4-(4'-methylphenyl)butanoic acid HCl; (R)-4-(4-Methylphenyl)-3-aminobutanoic acid hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-3-Amino-4-(4-Methylphenyl)Butanoic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.