Description

Chloro{(1R,2R)-(+)-2-Amino-1,2-DiphenylethylAmido}(p-Cymene)Ruthenium(II) is a highly specialized, chiral ruthenium-based organometallic catalyst. This compound matters for its exceptional efficiency and selectivity in facilitating asymmetric hydrogenation and transfer hydrogenation reactions, which are critical for producing single-enantiomer intermediates. Pharmaceutical R&D laboratories and fine chemical manufacturers need this high-performance catalyst to synthesize optically pure active pharmaceutical ingredients (APIs) and advanced agrochemicals with precise stereochemical control.

Application

• Asymmetric Hydrogenation Catalyst: For the enantioselective reduction of prochiral ketones, imines, and olefins in pharmaceutical synthesis.
• Transfer Hydrogenation Reactions: Enables the use of alternative hydrogen donors like isopropanol or formic acid for safer and more scalable processes.
• Synthesis of Chiral Amines and Alcohols: Production of key chiral building blocks for APIs, such as β-amino alcohols and substituted amines.
• Agrochemical Intermediate Manufacturing: Used in the creation of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Academic and Industrial R&D: A valuable tool for developing new catalytic methodologies and exploring novel synthetic routes in process chemistry.
• Production of Specialty Flavors and Fragrances: For the asymmetric synthesis of chiral odorants and flavoring agents.

Basic Information

Product Name	Chloro{(1R,2R)-(+)-2-Amino-1,2-DiphenylethylAmido}(p-Cymene)Ruthenium(II)
CAS No.	177552-91-9
Molecular Formula	C31H35ClN2O2RuS
Molecular Weight	634.21 g/mol
Synonyms	(R,R)-TsDPEN-Ru(p-cymene)Cl; (R,R)-N-(p-Toluenesulfonyl)-1,2-diphenylethylenediamine Ruthenium (p-cymene) Chloride; (R,R)-Ru-TsDPEN(p-cymene)Cl; (1R,2R)-N-(p-Toluenesulfonyl)-1,2-diphenylethylenediamine Ruthenium(II) Chloride (p-cymene) Complex; (R,R)-RuCl(p-cymene)(TsDPEN); Noyori-Ikariya Catalyst (Ru(II)-TsDPEN type); Asymmetric Transfer Hydrogenation Catalyst (R,R)-Ru-TsDPEN; Ruthenium(II) (η6-p-cymene)chloride[(1R,2R)-N-(p-tolylsulfonyl)-1,2-diphenylethylenediamine]
EINECS	Contact for details

Quality Control

Our high-purity organometallic catalysts are produced under strict quality management systems to ensure batch-to-batch consistency and optimal catalytic performance. Each lot undergoes comprehensive analysis, including HPLC purity assay, chiral purity verification, and elemental analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and relevant spectroscopic data to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to maintain stability and prevent decomposition. This compound is light-sensitive and easily oxidized; prolonged exposure to air, moisture, or ambient temperature should be avoided.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Ruthenium Content	15.5 - 16.5 %
Solubility	Soluble in dichloromethane, chloroform, toluene

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.