Description

n-1-Fmoc-1,5-Diaminopentane Hcl is a protected diamine building block, specifically designed for solid-phase peptide synthesis (SPPS) and other organic synthesis applications. Its core value lies in providing a primary amine for chain elongation while the Fmoc group offers orthogonal protection for the secondary amine, enabling precise and sequential synthesis. This compound is essential for researchers and manufacturers in pharmaceutical development, particularly for creating complex peptide-based therapeutics and diagnostic agents. Its reliable quality ensures reproducibility in critical synthetic pathways.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled, sequential assembly of peptide chains using Fmoc-chemistry protocols.
• Pharmaceutical Intermediates: Serves as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs), especially for peptide drugs.
• Bioconjugation and Linker Chemistry: Used to introduce spacer arms or functional handles for attaching peptides to carriers, surfaces, or other molecules.
• Combinatorial Chemistry: Employed in the generation of diverse chemical libraries for drug discovery and screening purposes.
• Organic Synthesis Reagent: Acts as a protected diamine nucleophile in various amide bond formation and coupling reactions.
• Research & Development: Fundamental reagent in academic and industrial R&D labs for exploring new synthetic methodologies and novel bioactive compounds.

Basic Information

Product Name	n-1-Fmoc-1,5-Diaminopentane Hcl
CAS No.	177333-17-4
Molecular Formula	C₂₁H₂₇ClN₂O₂
Molecular Weight	374.90 g/mol
Synonyms	1,5-Diaminopentane, N1-[(9H-fluoren-9-ylmethoxy)carbonyl]-, hydrochloride; N1-Fmoc-1,5-diaminopentane hydrochloride; Nα-Fmoc-cadaverine hydrochloride; Fmoc-Cad-OH·HCl; Fmoc-1,5-diaminopentane HCl; 5-[(9-Fluorenylmethoxycarbonyl)amino]pentylamine hydrochloride; N-(5-Aminopentyl)-9H-fluoren-9-ylmethoxycarboxamide hydrochloride
EINECS	Contact for details

Quality Control

Our n-1-Fmoc-1,5-Diaminopentane Hcl is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with cGMP, ISO, and other relevant quality standards for pharmaceutical intermediates. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.