Description

(S)-Methyl 2-Amino-4-Bromobutanoate Hbr is a high-purity chiral building block and synthetic intermediate of significant importance in pharmaceutical research and development. Its value lies in its role as a key precursor for the synthesis of complex molecules, particularly those with potential biological activity. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for applications in medicinal chemistry and asymmetric synthesis.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery.
• Peptidomimetics Synthesis: Used in the construction of non-natural amino acid derivatives and peptide analogs to enhance metabolic stability and bioavailability.
• Asymmetric Synthesis: Serves as a starting material for the preparation of other enantiomerically pure compounds via further functional group transformations.
• Agrochemical Research: Employed in the development of new chiral pesticides and herbicides where specific stereochemistry is required for efficacy.
• Ligand and Catalyst Development: Can be utilized to create novel chiral ligands for asymmetric catalysis or as a scaffold for molecular recognition studies.
• Academic & Institutional Research: A valuable tool for synthetic methodology development and chemical biology studies in university and government laboratories.

Basic Information

Product Name	(S)-Methyl 2-Amino-4-Bromobutanoate Hbr
CAS No.	177325-78-9
Molecular Formula	C5H10BrNO2 • HBr
Molecular Weight	277.0 g/mol
Synonyms	(S)-Methyl 2-Amino-4-bromobutyrate Hydrobromide; (S)-Methyl 4-Bromo-2-aminobutanoate HBr; L-2-Amino-4-bromobutyric acid methyl ester hydrobromide; Methyl (2S)-2-amino-4-bromobutanoate hydrobromide; (S)-Methyl 4-bromo-2-aminobutanoate hydrobromide salt; (S)-Me-4-Br-Abu-OMe•HBr; (S)-Methyl α-amino-γ-bromobutyrate HBr
EINECS	Contact for details

Quality Control

Our (S)-Methyl 2-Amino-4-Bromobutanoate Hbr is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-purity standards for research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.