Description

(R)-(+)-6-Methoxy 2-Aminotetralin CAS NO 177017-68-4 is a high-purity chiral intermediate of significant importance in pharmaceutical research and development. This compound serves as a critical building block for the synthesis of active pharmaceutical ingredients (APIs) targeting neurological and cardiovascular systems. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutics, particularly those requiring enantiomerically pure components for optimal efficacy and safety profiles.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug molecules, particularly for central nervous system (CNS) active compounds.
• Neurological Research: Used in the development and study of dopaminergic and serotonergic agents for potential treatment of disorders like Parkinson's disease and depression.
• Cardiovascular Drug Development: Employed as a precursor in the synthesis of compounds with potential vasodilatory or antihypertensive properties.
• Asymmetric Synthesis: Utilized in chiral pool synthesis and catalytic asymmetric reactions to construct complex molecular architectures with high enantiomeric excess.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Chemical Biology Probes: Acts as a scaffold for developing molecular probes to study receptor-ligand interactions and signal transduction pathways.

Basic Information

Product Name	(R)-(+)-6-Methoxy 2-Aminotetralin
CAS No.	177017-68-4
Molecular Formula	C11H15NO
Molecular Weight	177.24 g/mol
Synonyms	(R)-6-Methoxy-1,2,3,4-tetrahydronaphthalen-2-amine; (R)-(+)-6-Methoxy-2-aminotetralin; (2R)-6-Methoxy-1,2,3,4-tetrahydronaphthalen-2-amine; (R)-6-Methoxy-2-tetralinamine; (R)-MAT; (R)-6-MAT; (R)-6-Methoxy-2-ATN; (R)-2-Amino-6-methoxytetralin
EINECS	Contact for details

Quality Control

Our (R)-(+)-6-Methoxy 2-Aminotetralin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric purity, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.