Description

6,8-Dioxabicyclo[3.2.1]Oct-2-Ene-2-Carboxaldehyde, 4-Oxo-, (1S)- (9Ci) is a high-purity, stereochemically defined bicyclic aldehyde building block. This compound is valued for its unique fused ring structure and reactive aldehyde and ketone functionalities, making it a versatile chiral synthon for complex organic synthesis. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the construction of novel active ingredients and natural product analogs.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of complex drug candidates, particularly those requiring fused oxygen-containing heterocycles.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides where its specific stereochemistry and functional groups are critical for bioactivity.
• Asymmetric Synthesis: Serves as a sophisticated starting material or intermediate in catalytic asymmetric reactions to introduce chirality into target molecules.
• Natural Product Synthesis: Employed in the total synthesis of complex natural products containing similar bicyclic or polyether motifs.
• Material Science Research: Investigated as a monomer or cross-linking agent for creating novel polymers with specific architectural features.
• Chemical Biology Probes: Utilized to develop molecular probes for studying enzyme mechanisms or biological pathways due to its reactive aldehyde handle.

Basic Information

Product Name	6,8-Dioxabicyclo[3.2.1]Oct-2-Ene-2-Carboxaldehyde, 4-Oxo-, (1S)- (9Ci)
CAS No.	176912-65-5
Molecular Formula	C8H8O4
Molecular Weight	168.15 g/mol
Synonyms	(1S)-4-Oxo-6,8-dioxabicyclo[3.2.1]oct-2-ene-2-carboxaldehyde; (1S)-4-Oxo-6,8-dioxabicyclo[3.2.1]oct-2-ene-2-carbaldehyde; (1S)-4-Oxo-6,8-dioxabicyclo[3.2.1]oct-2-en-2-carboxaldehyde; 6,8-Dioxabicyclo[3.2.1]oct-2-ene-2-carboxaldehyde, 4-oxo-, (1S)-; (1S)-4-Oxo-6,8-dioxabicyclo[3.2.1]oct-2-en-2-carbaldehyde; (1S)-4-Oxo-6,8-dioxabicyclo[3.2.1]oct-2-ene-2-carboxylic aldehyde; (1S)-4-Oxo-6,8-dioxabicyclo[3.2.1]oct-2-en-2-carboxaldehyde (9CI)
EINECS	Contact for details

Quality Control

Our 6,8-Dioxabicyclo[3.2.1]Oct-2-Ene-2-Carboxaldehyde, 4-Oxo-, (1S)- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing all specifications are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This material is easily oxidized and light-sensitive. Allow the sealed container to reach ambient temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.