Description

4-(Bromomethyl)-8-Fluoroquinolin-2(1H)-One is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters because its unique structure, featuring both a reactive bromomethyl handle and a fluorinated quinolinone core, enables the targeted construction of complex molecules with potential biological activity. Pharmaceutical researchers and fine chemical manufacturers need it for developing novel active pharmaceutical ingredients (APIs), agrochemicals, and other specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel fluoroquinolone-based antibiotics and other therapeutic agents targeting bacterial infections.
• Agrochemical Development: Used in research to create new fungicides and herbicides, leveraging the bioactivity of the quinolinone scaffold.
• Chemical Biology Probe Synthesis: Serves as a versatile scaffold for constructing molecular probes to study enzyme function and biological pathways.
• Material Science Research: Employed in the development of advanced organic materials, such as ligands for metal-organic frameworks (MOFs) or functional polymers.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring precise functionalization of the quinolinone ring system.

Basic Information

Product Name	4-(Bromomethyl)-8-Fluoroquinolin-2(1H)-One
CAS No.	176912-29-1
Molecular Formula	C₁₁H₇BrFNO
Molecular Weight	268.08 g/mol
Synonyms	8-Fluoro-4-(bromomethyl)-1,2-dihydro-2-oxoquinoline; 8-Fluoro-4-(bromomethyl)-2(1H)-quinolinone; 4-(Bromomethyl)-8-fluoro-1H-quinolin-2-one; 8-Fluoro-4-(bromomethyl)quinolin-2(1H)-one; 176912-29-1; 4-Bromomethyl-8-fluoroquinolin-2(1H)-one
EINECS	Contact for details

Quality Control

Our 4-(Bromomethyl)-8-Fluoroquinolin-2(1H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling should be performed under appropriate conditions to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.