Description

4-(1-Methyl-1-Nitroethyl)Tetrahydrofuran-2-One is a specialized nitro-substituted lactone building block of significant interest in advanced organic synthesis. This compound matters for its role as a key chiral intermediate, enabling the construction of complex molecular architectures with high stereochemical control. Pharmaceutical, agrochemical, and fine chemical R&D laboratories need it for developing novel active ingredients, particularly in the synthesis of nitrogen-containing heterocycles and other high-value target molecules.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially those containing nitro or lactone functional groups.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its unique structure contributes to biological activity.
• Fine Chemical Manufacturing: Serves as a versatile building block for creating complex, high-value specialty chemicals and flavors/fragrances.
• Academic & Industrial Research: A valuable reagent in methodological development and synthetic chemistry research within universities and corporate R&D centers.
• Material Science Precursor: Potential use in the synthesis of novel polymers or functional materials with specific chemical properties.

Basic Information

Product Name	4-(1-Methyl-1-Nitroethyl)Tetrahydrofuran-2-One
CAS No.	176793-53-6
Molecular Formula	C7H11NO4
Molecular Weight	173.17 g/mol
Synonyms	4-(1-Methyl-1-nitroethyl)dihydrofuran-2(3H)-one; 4-(1-Methyl-1-nitroethyl)butyrolactone; 2-Oxotetrahydrofuran-4-yl(1-nitroethyl)ethane; 4-(α-Methyl-α-nitroethyl)-γ-butyrolactone; 4-(1-Nitro-1-methylethyl)tetrahydro-2-furanone; Nitro-substituted butyrolactone derivative; CAS 176793-53-6
EINECS	Contact for details

Quality Control

Our 4-(1-Methyl-1-Nitroethyl)Tetrahydrofuran-2-One is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay, chiral purity, and impurity profiles to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (typical)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.