Description

7-Bromo-2-Trifluoromethylquinoline is a high-value, multi-functional halogenated quinoline derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in the strategic combination of a bromine substituent and a trifluoromethyl group, which enables precise molecular modifications to enhance the biological activity and physicochemical properties of target compounds. This intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors, antiviral agents, and anti-inflammatory compounds.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group can improve metabolic stability and bioavailability.
• Material Science Research: Serves as a building block for creating organic light-emitting diodes (OLEDs) and other electronic materials due to the quinoline scaffold's electron-transport properties.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions, such as Suzuki or Buchwald-Hartwig amination.
• Fluorine Chemistry Studies: Acts as a model compound for investigating the effects of fluorine substitution on aromatic systems in medicinal and synthetic chemistry.

Basic Information

Product Name	7-Bromo-2-Trifluoromethylquinoline
CAS No.	176722-72-8
Molecular Formula	C₁₀H₅BrF₃N
Molecular Weight	276.05 g/mol
Synonyms	7-Bromo-2-(trifluoromethyl)quinoline; 2-(Trifluoromethyl)-7-bromoquinoline; Quinoline, 7-bromo-2-(trifluoromethyl)-; 7-Bromo-2-trifluoromethyl-quinoline; 176722-72-8; 7-Bromo-2-trifluoromethylquinoline; 7-Bromo-2-(trifluoromethyl)quinoline
EINECS	Contact for details

Quality Control

Our 7-Bromo-2-Trifluoromethylquinoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity assessment and NMR for structural confirmation, to meet the stringent requirements of research and scale-up applications. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in a dark place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.