Description

5-Bromo-2-(Trifluoromethyl)Quinoline is a high-purity, halogenated quinoline derivative serving as a critical advanced intermediate in modern synthetic chemistry. Its core value lies in the strategic combination of a bromine substituent and a trifluoromethyl group, enabling precise functionalization and the introduction of desirable physicochemical properties into target molecules. This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and materials science industries who require reliable building blocks for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the development of organic electronic materials, such as OLEDs and semiconductors, due to its electron-deficient quinoline core.
• Ligand and Catalyst Development: Employed in the creation of novel nitrogen-based ligands for transition metal catalysis, facilitating challenging cross-coupling and other synthetic transformations.
• Fluorescent Probe and Dye Chemistry: Acts as a core structure for synthesizing specialized fluorescent tags and dyes used in bio-imaging and analytical sensing applications.

Basic Information

Product Name	5-Bromo-2-(Trifluoromethyl)Quinoline
CAS No.	176722-71-7
Molecular Formula	C10H5BrF3N
Molecular Weight	276.06 g/mol
Synonyms	2-(Trifluoromethyl)-5-bromoquinoline; 5-Bromo-2-trifluoromethylquinoline; Quinoline, 5-bromo-2-(trifluoromethyl)-; 176722-71-7; 5-Bromo-2-(trifluoromethyl)quinoline; 5-Bromo-2-(trifluoromethyl)chinolin; 5-Bromo-2-(trifluorométhyl)quinoléine
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-2-(Trifluoromethyl)Quinoline is manufactured under a strict quality management system and undergoes rigorous analytical testing to ensure consistency and high purity. Our standard grade meets specifications suitable for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.