Description

7-[2-Cyclopropyl-4-(4-Fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoic acid is a key synthetic intermediate in the production of advanced pharmaceutical compounds. Its complex, multi-functional structure makes it a critical building block for active pharmaceutical ingredients (APIs) targeting specific metabolic pathways. This high-purity intermediate is essential for manufacturers in the pharmaceutical and advanced fine chemical sectors requiring precise molecular architecture for research and commercial synthesis.

Application

• Pharmaceutical Intermediate: Primary use as a critical building block in the synthesis of statin-class or related lipid-regulating active pharmaceutical ingredients (APIs).
• Research & Development: Serves as a key starting material or intermediate in medicinal chemistry programs for novel therapeutic agent discovery.
• Process Chemistry: Used in scale-up and optimization studies for the commercial manufacturing of complex drug molecules.
• Reference Standard: High-purity grades are utilized as analytical reference standards for quality control and method validation in API production.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of other complex, high-value specialty chemicals with quinoline and fluorophenyl motifs.

Basic Information

Product Name	7-[2-Cyclopropyl-4-(4-Fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoic acid
CAS No.	176593-07-0
Molecular Formula	C28H28FNO4
Molecular Weight	461.53 g/mol
Synonyms	7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]-3,5-dihydroxy-6-heptenoic acid; (3R,5R)-7-[2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoic acid; Pitavastatin intermediate; NK-104 intermediate; Livalo intermediate; 7-(2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-3,5-dihydroxyhept-6-enoic Acid; 176593-07-0
EINECS	Contact for details

Quality Control

Our 7-[2-Cyclopropyl-4-(4-Fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoic acid is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH limits
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.