Description

4-Iodobenzothiophene-2-Carboxylic Acid is a high-purity iodinated heterocyclic building block of significant value in advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and materials science. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators with enhanced activity.
• Material Science: Serves as a building block for organic semiconductors, liquid crystals, and other functional organic materials.
• Chemical Biology: Employed as a probe or tag in bioconjugation and labeling studies due to the reactivity of the iodine moiety.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Heck couplings to introduce the benzothiophene scaffold.
• Academic & Contract Research: Utilized in universities and CROs for methodological development and exploratory synthesis projects.

Basic Information

Product Name	4-Iodobenzothiophene-2-Carboxylic Acid
CAS No.	176549-83-0
Molecular Formula	C9H5IO2S
Molecular Weight	304.10 g/mol
Synonyms	4-Iodo-1-benzothiophene-2-carboxylic acid; 4-Iodobenzo[b]thiophene-2-carboxylic Acid; 2-Carboxy-4-iodobenzothiophene; 4-Iodo-2-benzothiophenecarboxylic Acid; 176549-83-0; 4-Iodobenzo[b]thiophene-2-carboxylate
EINECS	Contact for details

Quality Control

Every batch of 4-Iodobenzothiophene-2-Carboxylic Acid is produced and tested under strict quality management protocols. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.