Description

3-{[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino}-5-Hydroxybenzoic Acid CAS NO 176442-21-0 is a high-purity, protected amino acid derivative primarily used as a critical building block in solid-phase peptide synthesis (SPPS). Its core value lies in enabling the controlled assembly of complex peptides and peptidomimetics for research and pharmaceutical development. This compound is essential for researchers and manufacturers in the fields of medicinal chemistry, biochemistry, and drug discovery who require reliable, high-quality intermediates for producing therapeutic peptides and investigating protein-protein interactions.

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a key Fmoc-protected amino acid building block for the sequential assembly of custom peptide sequences.
• Pharmaceutical Intermediates: Used in the research and development of novel peptide-based therapeutics, including hormone analogs and enzyme inhibitors.
• Bioconjugation and Labeling: The carboxylic acid and phenolic hydroxyl groups provide handles for conjugation to other molecules, carriers, or fluorescent tags.
• Combinatorial Chemistry Libraries: Employed in the generation of diverse compound libraries for high-throughput screening in drug discovery campaigns.
• Academic and Institutional Research: A vital reagent for studying peptide structure, function, and stability in university and government laboratories.
• Production of Custom Peptides: Used by CROs (Contract Research Organizations) and CDMOs (Contract Development and Manufacturing Organizations) for client-specific peptide manufacturing.

Basic Information

Product Name	3-{[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino}-5-Hydroxybenzoic Acid
CAS No.	176442-21-0
Molecular Formula	C22H17NO5
Molecular Weight	375.37 g/mol
Synonyms	Fmoc-3-Amino-5-hydroxybenzoic acid; 3-[(Fmoc)amino]-5-hydroxybenzoic acid; 5-Hydroxy-3-[(9H-fluoren-9-ylmethoxy)carbonylamino]benzoic acid; 3-(Fmoc-amino)-5-hydroxybenzoic acid; Fmoc-Abz(5-OH)-OH; Fmoc-3-Abz(5-OH)-OH; 3-Amino-5-hydroxybenzoic acid Fmoc derivative; N-Fmoc-3-amino-5-hydroxybenzoic acid
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, impurities, and other critical parameters are available upon request. We adhere to strict quality management protocols suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.