Description

6-Oxabicyclo[3.1.0]Hexane-1-Methanol is a high-value, strained bicyclic ether alcohol that serves as a versatile and critical chiral building block in advanced organic synthesis. Its unique oxabicyclo[3.1.0]hexane scaffold provides a rigid, three-dimensional framework essential for constructing complex molecular architectures with precise stereochemistry. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where its bicyclic structure imparts specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to control stereoselectivity.
• Material Science Research: Employed in the synthesis of specialty polymers, resins, and functional materials requiring rigid, oxygen-containing heterocyclic units.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry, including ring-opening reactions and cycloadditions.
• Fine Chemical Production: Utilized in the custom synthesis of complex, high-value specialty chemicals for various technological applications.

Basic Information

Product Name	6-Oxabicyclo[3.1.0]Hexane-1-Methanol
CAS No.	176300-40-6
Molecular Formula	C7H10O2
Molecular Weight	126.15 g/mol
Synonyms	(1S,5R)-6-Oxabicyclo[3.1.0]hexan-1-ylmethanol; (1S,5R)-6-Oxabicyclo[3.1.0]hexane-1-methanol; 1-(Hydroxymethyl)-6-oxabicyclo[3.1.0]hexane; 6-Oxabicyclo[3.1.0]hexane-1-methanol, (1S,5R)-rel-; Bicyclo[3.1.0]hexane-1-methanol, 6-oxa-; 6-Oxa-3-azabicyclo[3.1.0]hexane-3-carboxylic acid tert-butyl ester related compound
EINECS	Contact for details

Quality Control

Our 6-Oxabicyclo[3.1.0]Hexane-1-Methanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.