Description

(1S,2R,9R)-2-Methyl-Octahydro-2H-Quinolizidine-1-Methanol is a high-purity, stereochemically defined alkaloid derivative with a quinolizidine core structure. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, offering significant value for the development of complex molecules. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for applications in medicinal chemistry, process development, and the synthesis of bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in alkaloid-based drug discovery.
• Medicinal Chemistry Research: Used as a scaffold or precursor in the synthesis of compounds for biological screening and structure-activity relationship (SAR) studies.
• Asymmetric Synthesis: Employed as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce stereoselectivity.
• Agrochemical Development: Serves as an intermediate in the synthesis of advanced crop protection agents and pesticides.
• Fine Chemical Production: Utilized in the multi-step synthesis of complex, high-value specialty chemicals and flavors/fragrances.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic synthesis and natural product chemistry within university and corporate laboratories.

Basic Information

Product Name	(1S,2R,9R)-2-Methyl-Octahydro-2H-Quinolizidine-1-Methanol
CAS No.	176210-35-8
Molecular Formula	C11H21NO
Molecular Weight	183.29 g/mol
Synonyms	(1S,2R,9R)-2-Methyl-1-(hydroxymethyl)quinolizidine; (1S,2R,9R)-1-(Hydroxymethyl)-2-methylquinolizidine; 2-Methyl-1-quinolizidinemethanol, (1S,2R,9R)-; (-)-Cytisine derivative; Quinolizidine methanol derivative; Chiral quinolizidine alcohol; (1S,2R,9R)-2-Methyloctahydro-2H-quinolizine-1-methanol
EINECS	Contact for details

Quality Control

Our (1S,2R,9R)-2-Methyl-Octahydro-2H-Quinolizidine-1-Methanol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.