Description

1-(Benzyloxy)-3,5-Difluorobenzene is a high-purity fluorinated aromatic ether building block of significant importance in advanced organic synthesis. Its core value lies in its unique molecular structure, which incorporates both a benzyl-protecting group and strategically placed fluorine atoms, making it a versatile intermediate for constructing complex molecules. This compound is primarily needed by research and development chemists and process scale-up teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the difluorobenzene moiety can enhance biological activity and metabolic stability.
• Liquid Crystal Materials: Serves as a precursor in the development of fluorinated liquid crystals for high-performance displays.
• Organic Electronics: Employed in the synthesis of charge-transport materials and semiconductors for OLEDs and other electronic devices.
• Chemical Research: A valuable building block for academic and industrial research in cross-coupling reactions and medicinal chemistry.
• Fluorine Chemistry: Used to introduce fluorine atoms and benzyl-protected phenolic groups into more complex molecular architectures.

Basic Information

Product Name	1-(Benzyloxy)-3,5-Difluorobenzene
CAS No.	176175-97-6
Molecular Formula	C13H10F2O
Molecular Weight	220.22 g/mol
Synonyms	3,5-Difluorophenyl benzyl ether; Benzyl 3,5-difluorophenyl ether; 3,5-Difluorophenyl Benzyl Ether; 1-(Benzyloxy)-3,5-difluorobenzene; (3,5-Difluorophenoxy)methyl]benzene; 3,5-Difluorophenol benzyl ether; BDFB; NSC 405124
EINECS	Contact for details

Quality Control

Our 1-(Benzyloxy)-3,5-Difluorobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.