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Phenylmethyl o-(n-Acetyl-α-Neuraminosyl)-3-o-(β-D-Galactopyranosyl)-4-[2-(Acetylamino)-2-Deoxy]-β-D-Glucopyranoside CAS NO 176166-22-6
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CAS No.:176166-22-6
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Phenylmethyl o-(n-Acetyl-α-Neuraminosyl)-3-o-(β-D-Galactopyranosyl)-4-[2-(Acetylamino)-2-Deoxy]-β-D-Glucopyranoside is a complex, high-purity carbohydrate derivative of significant interest in advanced biochemical research and pharmaceutical development. This compound serves as a critical intermediate and reference standard for the synthesis and study of sialylated glycoconjugates, which are pivotal in cellular recognition and signaling processes. It is essential for researchers and manufacturers in the fields of glycobiology, vaccine development, and targeted therapeutic agents.
Application
- Glycobiology Research: As a key intermediate for studying sialic acid-containing oligosaccharides and their role in cell-cell interactions, pathogen recognition, and immune response modulation.
- Pharmaceutical Intermediates: Used in the synthesis of novel glycoconjugate vaccines and biotherapeutics targeting cancer, infectious diseases, and inflammatory disorders.
- Enzymology Studies: Serves as a substrate or inhibitor for sialyltransferases, neuraminidases, and other glycosyltransferases to elucidate enzyme mechanisms and kinetics.
- Diagnostic Reagent Development: Employed in the creation of high-specificity assays and diagnostic tools for detecting disease-related glycan biomarkers.
- Reference Standard: Provides a certified standard for quality control and analytical method validation (HPLC, MS, NMR) in carbohydrate chemistry.
- Chemical Biology Probes: Utilized to develop labeled probes for imaging and tracking glycan expression and localization in biological systems.
Basic Information
| Product Name | Phenylmethyl o-(n-Acetyl-α-Neuraminosyl)-3-o-(β-D-Galactopyranosyl)-4-[2-(Acetylamino)-2-Deoxy]-β-D-Glucopyranoside |
| CAS No. | 176166-22-6 |
| Molecular Formula | C36H54N2O21 |
| Molecular Weight | 850.82 g/mol |
| Synonyms | Benzyl 5-acetamido-3,5-dideoxy-α-D-glycero-D-galacto-non-2-ulopyranosylonate-(2→3)-β-D-galactopyranosyl-(1→4)-2-acetamido-2-deoxy-β-D-glucopyranoside; Benzyl α-Neu5Ac-(2→3)-β-Gal-(1→4)-β-GlcNAc; Sialyl Lewis X (sLeX) Glycoside Derivative; Benzyl Sialyllactosamine; Complex Carbohydrate Derivative; Glycoconjugate Intermediate; Sialylated Trisaccharide Benzyl Glycoside |
| EINECS | Contact for details |
Quality Control
Our Phenylmethyl o-(n-Acetyl-α-Neuraminosyl)-3-o-(β-D-Galactopyranosyl)-4-[2-(Acetylamino)-2-Deoxy]-β-D-Glucopyranoside is produced under stringent quality management systems. Each batch undergoes comprehensive analytical characterization using techniques including NMR, HPLC, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific research or cGMP guidelines for pharmaceutical intermediates.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This compound is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider desiccation and storage under an inert atmosphere to maintain stability.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (HPLC) | Conforms to reference standard |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 95.0% |
| Water Content (KF) | ≤ 5.0% |
| Residual Solvents (GC) | Meets ICH guidelines |
| Specific Rotation | Contact for details |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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