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Phenylmethyl o-(n-Acetyl-α-Neuraminosyl)-3-o-(β-D-Galactopyranosyl)-4-[2-(Acetylamino)-2-Deoxy]-β-D-Glucopyranoside CAS NO 176166-22-6


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CAS No.:176166-22-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Phenylmethyl o-(n-Acetyl-α-Neuraminosyl)-3-o-(β-D-Galactopyranosyl)-4-[2-(Acetylamino)-2-Deoxy]-β-D-Glucopyranoside is a complex, high-purity carbohydrate derivative of significant interest in advanced biochemical research and pharmaceutical development. This compound serves as a critical intermediate and reference standard for the synthesis and study of sialylated glycoconjugates, which are pivotal in cellular recognition and signaling processes. It is essential for researchers and manufacturers in the fields of glycobiology, vaccine development, and targeted therapeutic agents.

Application

  • Glycobiology Research: As a key intermediate for studying sialic acid-containing oligosaccharides and their role in cell-cell interactions, pathogen recognition, and immune response modulation.
  • Pharmaceutical Intermediates: Used in the synthesis of novel glycoconjugate vaccines and biotherapeutics targeting cancer, infectious diseases, and inflammatory disorders.
  • Enzymology Studies: Serves as a substrate or inhibitor for sialyltransferases, neuraminidases, and other glycosyltransferases to elucidate enzyme mechanisms and kinetics.
  • Diagnostic Reagent Development: Employed in the creation of high-specificity assays and diagnostic tools for detecting disease-related glycan biomarkers.
  • Reference Standard: Provides a certified standard for quality control and analytical method validation (HPLC, MS, NMR) in carbohydrate chemistry.
  • Chemical Biology Probes: Utilized to develop labeled probes for imaging and tracking glycan expression and localization in biological systems.

Basic Information

Product Name Phenylmethyl o-(n-Acetyl-α-Neuraminosyl)-3-o-(β-D-Galactopyranosyl)-4-[2-(Acetylamino)-2-Deoxy]-β-D-Glucopyranoside
CAS No. 176166-22-6
Molecular Formula C36H54N2O21
Molecular Weight 850.82 g/mol
Synonyms Benzyl 5-acetamido-3,5-dideoxy-α-D-glycero-D-galacto-non-2-ulopyranosylonate-(2→3)-β-D-galactopyranosyl-(1→4)-2-acetamido-2-deoxy-β-D-glucopyranoside; Benzyl α-Neu5Ac-(2→3)-β-Gal-(1→4)-β-GlcNAc; Sialyl Lewis X (sLeX) Glycoside Derivative; Benzyl Sialyllactosamine; Complex Carbohydrate Derivative; Glycoconjugate Intermediate; Sialylated Trisaccharide Benzyl Glycoside
EINECS Contact for details

Quality Control

Our Phenylmethyl o-(n-Acetyl-α-Neuraminosyl)-3-o-(β-D-Galactopyranosyl)-4-[2-(Acetylamino)-2-Deoxy]-β-D-Glucopyranoside is produced under stringent quality management systems. Each batch undergoes comprehensive analytical characterization using techniques including NMR, HPLC, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific research or cGMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This compound is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider desiccation and storage under an inert atmosphere to maintain stability.

Specification

Item Specification
Appearance White to off-white solid
Identification (HPLC) Conforms to reference standard
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 5.0%
Residual Solvents (GC) Meets ICH guidelines
Specific Rotation Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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