Description

7-Nitro-1,2,3,4-Tetrahydro-Naphthalen-2-Ylamine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS number 175871-06-4. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers for the development of central nervous system (CNS) active compounds and other specialized APIs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting neurological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic entities.
• Fine Chemical Synthesis: Serves as a precursor for more complex, functionalized tetralin and naphthalene derivatives.
• Academic & Contract Research: Utilized in university and CRO settings for exploratory research in organic and heterocyclic chemistry.
• Process Development: Employed in scaling up synthetic routes from laboratory to pilot plant scale for potential commercial production.

Basic Information

Product Name	7-Nitro-1,2,3,4-Tetrahydro-Naphthalen-2-Ylamine Hydrochloride
CAS No.	175871-06-4
Molecular Formula	C₁₀H₁₃ClN₂O₂
Molecular Weight	228.67 g/mol
Synonyms	2-Amino-7-nitro-1,2,3,4-tetrahydronaphthalene hydrochloride; 7-Nitro-2-amino-1,2,3,4-tetrahydronaphthalene HCl; 7-Nitro-1,2,3,4-tetrahydro-2-naphthylamine hydrochloride; 2-Amino-7-nitro-1,2,3,4-tetrahydronaphthalene HCl; 7-Nitro-2-tetralinamine hydrochloride; 175871-06-4; 7-Nitro-2-ATN HCl
EINECS	Contact for details

Quality Control

Our 7-Nitro-1,2,3,4-Tetrahydro-Naphthalen-2-Ylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.