Description

8-Ethyl-3-Fluoro-2-Hydroxyquinoline is a fluorinated quinoline derivative that serves as a versatile and high-value synthetic intermediate. Its molecular structure, featuring both a fluorine atom and a hydroxyl group, makes it a critical building block for the development of advanced pharmaceuticals and agrochemicals. This compound is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in developing fluorinated quinolone antibiotics and other therapeutic agents targeting various diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides where the fluorine atom enhances biological activity and environmental stability.
• Organic Light-Emitting Diodes (OLEDs): Acts as a potential ligand or core structure in the development of electron-transporting or emissive materials for display and lighting technologies.
• Coordination Chemistry & Catalysis: Serves as a chelating ligand for metal complexes used in homogeneous catalysis and material science applications.
• Fluorescent Probe Development: Utilized in research to create sensitive fluorescent markers and sensors for biochemical and analytical applications.
• Academic & Industrial R&D: Fundamental building block in medicinal chemistry and organic synthesis research for exploring new chemical entities and reaction pathways.

Basic Information

Product Name	8-Ethyl-3-Fluoro-2-Hydroxyquinoline
CAS No.	175609-34-4
Molecular Formula	C₁₁H₁₀FNO
Molecular Weight	191.20 g/mol
Synonyms	3-Fluoro-8-ethyl-2-hydroxyquinoline; 2-Hydroxy-8-ethyl-3-fluoroquinoline; 8-Ethyl-3-fluoroquinolin-2-ol; 175609-34-4; 3-Fluoro-8-ethylquinolin-2-ol; 2-Quinolinol, 8-ethyl-3-fluoro-; 8-Ethyl-3-fluoro-2(1H)-quinolinone (tautomer)
EINECS	Contact for details

Quality Control

Our production of 8-Ethyl-3-Fluoro-2-Hydroxyquinoline adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP standards for pharmaceutical applications and can tailor purity grades to meet specific research or industrial requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to strong light should be avoided. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.