Description

3-[2-[(4-Chlorophenyl)Thio]-5-Nitrophenyl]Acrylic Acid is a specialized organic intermediate featuring a unique molecular scaffold combining chlorophenyl, nitrophenyl, and acrylic acid functionalities. This compound matters for its role as a critical building block in the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and agrochemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways.
• Agrochemical Research: Used in developing new herbicides, fungicides, or plant growth regulators that require its specific aromatic and acrylic acid structure.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers with tailored optical or electronic properties.
• Organic Synthesis Building Block: Utilized in Suzuki, Heck, or other cross-coupling reactions to create complex biaryl or conjugated systems for research purposes.
• Dye & Pigment Intermediate: Acts as a starting material for synthesizing specialized azo dyes or pigments due to its nitro and chromophore groups.
• Bioconjugation Chemistry: The acrylic acid moiety can be used for Michael addition reactions in bioconjugation and probe development.

Basic Information

Product Name	3-[2-[(4-Chlorophenyl)Thio]-5-Nitrophenyl]Acrylic Acid
CAS No.	175278-51-0
Molecular Formula	C15H10ClNO4S
Molecular Weight	335.76 g/mol
Synonyms	(E)-3-[2-[(4-Chlorophenyl)thio]-5-nitrophenyl]acrylic acid; 3-[2-[(4-Chlorophenyl)thio]-5-nitrophenyl]-2-propenoic acid; 2-Propenoic acid, 3-[2-[(4-chlorophenyl)thio]-5-nitrophenyl]-; (E)-3-(2-((4-Chlorophenyl)thio)-5-nitrophenyl)acrylic acid; 3-(2-((4-Chlorophenyl)sulfanyl)-5-nitrophenyl)acrylic acid; 175278-51-0; 3-[2-[(4-Chlorophenyl)sulfanyl]-5-nitrophenyl]prop-2-enoic acid
EINECS	Contact for details

Quality Control

Our 3-[2-[(4-Chlorophenyl)Thio]-5-Nitrophenyl]Acrylic Acid undergoes rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry to verify identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are available upon request. Our quality management system supports the needs of research and development under cGMP-like controls where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.