Description

3-(5-Bromo-2-Thienyl)Isoxazole is a high-purity brominated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of novel pharmaceuticals and agrochemicals, where its unique thienyl-isoxazole scaffold enables the creation of molecules with targeted biological activity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to incorporate complex, functionalized heterocycles into their molecular designs.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders or anti-infective agents.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, or insecticides, leveraging the bioactivity of the thiophene and isoxazole motifs.
• Material Science Precursor: Acts as a building block for organic electronic materials, such as organic semiconductors or light-emitting diodes (OLEDs), due to its conjugated system and bromine handle for further cross-coupling.
• Chemical Biology Probe Development: Employed in creating specialized molecular probes and inhibitors for studying enzyme function and biological pathways in academic and industrial research settings.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific custom synthesis projects requiring complex heterocyclic chemistry.

Basic Information

Product Name	3-(5-Bromo-2-Thienyl)Isoxazole
CAS No.	175205-66-0
Molecular Formula	C7H4BrNO2S
Molecular Weight	246.08 g/mol
Synonyms	5-Bromo-2-(isoxazol-3-yl)thiophene; 3-(5-Bromothiophen-2-yl)-1,2-oxazole; 3-(5-Bromo-2-thienyl)-1,2-oxazole; 3-(5-Bromothien-2-yl)isoxazole; 175205-66-0; 5-Bromo-2-(3-isoxazolyl)thiophene; 3-(5-Bromothiophene-2-yl)isoxazole
EINECS	Contact for details

Quality Control

Our 3-(5-Bromo-2-Thienyl)Isoxazole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.